adenylate cyclase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15658	KH7		cAMP , AChR
	KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific. It has IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays. KH7 is also a cAMP inhibito...		cAMP , AChR
T16938	ST034307		Adenylyl cyclase
	ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM).		Adenylyl cyclase
T60003	AC1-IN-1		Adenylyl cyclase
	AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).		Adenylyl cyclase
T10066	2',5'-Dideoxyadenosine		Adenylyl cyclase , Adrenergic Receptor , AChR
	2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).		Adenylyl cyclase , Adrenergic Receptor , AChR
T0322	Fipexide		Dopamine Receptor , AChR
	Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...		Dopamine Receptor , AChR
T16275	NB001	HTS 09836	Adenylyl cyclase
	NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.		Adenylyl cyclase
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
T8702	SKF-83566		Dopamine Receptor , 5-HT Receptor , AChR
	SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM		Dopamine Receptor , 5-HT Receptor , AChR
T0830	Bithionol	Actamer	cAMP , Parasite
	Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bit...		cAMP , Parasite
T2172	SQ22536	9-(tetrahydrofuran-2-yl)-9h-purin-6-amine,SQ 22536	AChR
	SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isola...		AChR
T80069	PACAP (6-27) (human, ovine, rat)	Pituitary adenylate cyclase-activating peptide (6-27)
	PACAP (6-27) (human, ovine, rat) serves as an antagonist for the PACAP receptor, inhibiting the catecholamine response of the canine adrenal gland to vasoactive intestinal peptide (VIP). This compound holds promise for r...
TP1878	PACAP (1-38), human, ovine, rat	Pituitary Adenylate Cyclase Activating Polypeptide 38,PACAP 1-38	PACAP
	PACAP (1-38), human, ovine, rat (Pituitary Adenylate Cyclase Activating Polypeptide 38) is a neuropeptide with 38 amino acid residues.		PACAP
TP1054	PACAP (1-38), human, ovine, rat TFA	Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP...
T11918	Lysipressin	Lysine vasopressin,[Lys8]-Vasopressin	Others
	Lysipressin ([Lys8]-Vasopressin), Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families.		Others
T14880	CB-7921220	6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid,6-(4-Aminostyryl)picolinic acid,6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid	AChR
	CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.		AChR
T23588	9-CP-Ade Mesylate	9-Cyclopentyladenine monomethanesulfonate,9 CP Ade Mesylate,9CPAde Mesylate	AChR
	9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.		AChR
T29652	9-Cyclopentyladenine	NSC19486,NSC 19486,9CPAde,9-CP-Ade,9 CP Ade,NSC-19486	AChR
	9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.		AChR
T1723	Adenosine 5'-diphosphate	Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite
	Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.		Endogenous Metabolite
T22489	2'-MeCCPA	2-Chloro-N-cyclopentyl-2′-C-methyladenosine	HCV Protease , Adenosine Receptor
	2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2'-MeCCPA ...		HCV Protease , Adenosine Receptor
T11918L	Lysipressin acetate(50-57-7(fb_acetate))	Lysine vasopressin acetate,[Lys8]-Vasopressin acetate	Others
	Lysipressin acetate(50-57-7(fb_acetate)) ([Lys8]-Vasopressin acetate) , Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been foun...		Others